Nuclear receptors (NRs) are important transcriptional modulators in metazoans. Typical NRs possess a conserved DNA binding domain (DBD) and a ligand binding domain (LBD). Since we discovered a type of novel NRs each of them has two DBDs and single LBD (2DBD-NRs) more than decade ago. there has been very few studies about 2DBD-NRs. https://www.jalyttlers.shop/product-category/kitchen-roll-holder/